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Our group studies bacterial mobile division and is particularly aiming to represent a ‘base up biology’ in synthetic cells that can autonomously divide. Our most important fascination lies in mobile division, chromatin construction, and spatial control.

Dynamics of initiation, termination and reinitiation of DNA translocation via the motor protein EcoR124I

Sculpting nano-electrodes that has a transmission electron beam for electrical and geometrical characterization of nanoparticles.

That may be a dream of mine and we set to operate having a mouth watering dose of naivety. This really is something which will most likely yield stunning brings about the lengthier expression, but that doesn't issue. You shouldn't only want to operate within the issues of tomorrow, but also within the issues of the day soon after tomorrow.’

Our analysis ranges from your biophysics of DNA to artificial cells and outside of. You should take a look under with the spectrum of our recent assignments.

All parameters were being the identical for every panel in this video clip, apart from the Original placement of your 6hb rod (shown in blue) within the nanopore. Simulations that terminated early as a consequence of translocation from the rod from the pore are marked by a gray background.

Learning DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.

Imagine if, in place of https://www.ceesdekker.net making use of conventional top rated-down silicon electronics, transistors may be constructed from The underside up utilizing one natural molecules given that the switching aspects? This concept, which grew to become The premise of right now’s industry of molecular electronics, 1st emerged in the seventies.

It absolutely was throughout this period that Dekker completed investigation on magnetic spin units and on sounds in superconductors and semiconductors.

Testing pseudotopological and nontopological types for SMC-pushed DNA loop extrusion towards roadblock-traversal experiments

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2008, initial observation of protein-coated DNA translocation via nanopores; settled the origin from the electrophoretic force on DNA in nanopores; found a substantial velocity improve of microtubules in electric fields; discovered an anomalous electro-hydrodynamic orientation of microtubules; and resolved the origin of sounds in carbon nanotubes in liquid

2004, discovery of recent physics in translocation of DNA by means of nanopores; initial experimental analyze of ions conduction in nanofluidic channels; initially electrochemistry with personal solitary-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; first electrical docking of microtubules on kinesin-coated nanostructures; initially biophysics characterization in the mechanical properties of double-stranded RNA; and to start with single-molecule analyze of DNA translocation by a restriction-modification enzyme.